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Celecoxib metabolism is primarily mediated via CYP2C9Three metabolitesa primary alcoholthe corresponding carboxylic acid and its glucuronide conjugatehave been identified in human plasmaThese metabolites are inactive as COX-1 or COX-2 inhibitors.

Medicines are sometimes prescribed for purposes other than those listed in a Medication GuideDo not use NSAIDs for a condition for which it was not prescribedDo not give NSAIDs to other peopleeven if they have the same symptoms that you haveIt may harm them.

The following adverse reactions are discussed in greater detail in other sections of the labeling:

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