We also saw the approval of Juluca, the first of our new two drug regimens in HIV, allowing us to establish a new paradigm in the treatment of this increasingly chronic disease.Within vaccines, we also continue to deliver good growth with sales up 6% at CER, the key drivers being meningitis and influenza vaccines, and their strong performance was partly offset by competition and pricing on some of our established vaccines. Season and competitive pressures in allergy, as well as divestments and the implementation of GST in India. Our power brands continue to deliver strong growth above market levels, and this has helped drive the margin improvements that Simon will talk you through shortly.At the group level, we delivered margin improvement of 40 basis points in CER terms as we improved cost and cash discipline while still investing behind our priority launches and R programs, including the investment in a priority review voucher to accelerate the introduction of Juluca.

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