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Antidepressant medications, including serotonergic medications like fluoxetine prozac , sertraline zoloft , paroxetine paxil , citalopram celexa , and escitalopram lexapro , are often prescribed because of their effectiveness and low incidence of side effects.
Information about Zoloft.
Drugs that interfere with serotonin reuptake inhibitionincluding ZOLOFTincrease the risk of bleeding eventsConcomitant use of aspirinnonsteroidal anti-inflammatory drugsNSAIDsother antiplatelet drugswarfarinand other anticoagulants may add to this riskCase reports and epidemiological studiescase-control and cohort designhave demonstrated an association between use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleedingBleeding events related to drugs that interfere with serotonin reuptake have ranged from ecchymosishematomaepistaxisand petechiae to life-threatening hemorrhages.
There was insufficient information to determine the effect of race or age on outcome in these studies.
Inform patients of the increased risk of bleeding associated with the concomitant use of ZOLOFT and antiplatelet agents or anticoagulantsFor patients taking warfarincarefully monitor the international normalized ratio.
Other infrequent adverse reactionsnot described elsewhere in the prescribing informationoccurring at an incidence of.
Advise the patient to read the FDA-approved patient labelingMedication Guide
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